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Home / Antibodies

CYP2D6 Antibody (R36473)

SKU : BHA17122696

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NSJ Bioreagents

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Mfr.No.	R36473-100UG
Clonality	Polyclonal (goat origin)
Description	CYP2D6, a member of the cytochrome P450 mixed-function oxidase system, is one of the most important enzymes involved in the metabolism of xenobiotics in the body. In particular, CYP2D6 is responsible for the metabolism and elimination of approximately 25% of clinically used drugs, via the addition or removal of certain functional groups specifically, hydroxylation, demethylation, and dealkylation at various points along a substrate's core structure. This enzyme also metabolizes several endogenous substances, such as hydroxytryptamines, neurosteroids, and both m-tyramine and p-tyramine which CYP2D6 metabolizes into dopamine in the brain and liver. (Wiki)
Formulation	0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide
Host	Goat
Immunogen Region	Amino acids PTGQPRPSHH were used as the immunogen for this CYP2D6 antibody.
Isotype	Goat Ig
Species Reactivity	Human
Note	Optimal dilution of the CYP2D6 antibody should be determined by the researcher.

Uniprot	P10635

Format	Antigen affinity purified
Purity	Antigen affinity
Storage	Aliquot and store the CYP2D6 antibody at -20oC.

Applications	ELISA (peptide), WB
Description	Western blot: 1-3ug/ml,ELISA (peptide) LOD: 1:1000

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17122696	R36473-100UG	100 ug	$399		Add to Cart

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