Transcription factor jun-B is a protein that in humans is encoded by the JUNB gene. It is mapped to 19p13.2. It is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA(CG)TCA-3', and a large fraction (over 50%) of the JUNB locus is contained in these flanking evolutionarily conserved sequences (FECS), which may be required for effecting the proper transcriptional regulation of this gene. Addtionally, the expression of JUNB gene might be involved in terminal granulocyte differentiation or in regulating granulocyte functionality.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
An amino acid sequence from the C-terminus of human JunB (QLKQKVMTHVSNGCQLLLGVKGHAF) was used as the immunogen for this JunB antibody (100% homologous in human, mouse and rat).
Isotype
IgG
Predicted Reactivity
Human, Mouse, Rat
Reactivity
Human, Mouse, Rat
Recombinant
No
Subcellular Location
Nuclear
Antigen
JunB
Gene Id
3726
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the JunB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Applications
IHC-P, WB
Dilution
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml