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Home / Antibodies

MMP2 Antibody (F53512)

SKU : BHA17119800

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NSJ Bioreagents

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Mfr.No.	F53512-0.1ML
Clonality	Monoclonal (mouse origin)
Description	Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-\|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. (UniProt)
Formulation	In ascites with 0.09% sodium azide
Host	Mouse
Immunogen Region	This MMP2 antibody was produced from mouse immunized with MMP2 recombinant protein.
Isotype	k, Mouse IgG2b
Species Reactivity	Human
Note	Titration of the MMP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Uniprot	P08253

Format	Ascites
Purity	Ascites
Storage	Aliquot the MMP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ELISA
Description	Western blot: 1:200-1:1000,IHC (Paraffin): 1:50-1:100

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119800	F53512-0.1ML	0.1 ml	$389		Add to Cart

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