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Home / Antibodies

Phospho-TSC2 Antibody (pT1462) (F53757)

SKU : BHA17119856

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NSJ Bioreagents

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Mfr.No.	F53757-0.4ML
Clonality	Polyclonal (rabbit origin)
Description	Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	This phospho-TSC2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT1462 of human TSC2.
Isotype	Rabbit Ig
Species Reactivity	Human
Note	Titration of the phospho-TSC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Uniprot	P49815

Format	Antigen affinity purified
Purity	Antigen affinity
Storage	Aliquot the phospho-TSC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	DB, ELISA
Description	Dot blot: 1:500

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119856	F53757-0.4ML	0.4 ml	$389		Add to Cart

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