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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD45RB Antibody

SKU : BHA17127899

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NSJ Bioreagents

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Mfr.No.	V9070IHC, V9070IHC-7ML
Clonality	Monoclonal (mouse origin)
Description	CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
Formulation	Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; For IHC use only
Host	Mouse
Immunogen Region	Human peripheral blood lymphocytes maintained in T cell growth factor were used as the immunogen for this anti-CD45RB antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	P08575

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the anti-CD45RB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/anti-cd45rb-antibody-spm569-v9070" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127899	V9070IHC, V9070IHC-7ML	7ml	$539		Add to Cart

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