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Home / Primary Antibodies / Monoclonal Antibodies

Apolipoprotein J Antibody / APO-J / Clusterin

SKU : BHA17123271

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NSJ Bioreagents

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Mfr.No.	V9375SAF, V9375SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Clusterin, also designated complement lysis inhibitor (CLI), apolipoprotein J (APOJ), sulfated glycoprotein 2 (SGP2), SP40 and testosterone-repressed prostate message 2 (TRPM2), is a secretory, heterodimeric glycoprotein that influences immune regulation, cell adhesion, transformation, lipid transportation, tissue remodeling, membrane recycling and cell-cell interactions. Clusterin is synthesized as a 449 amino acid polypeptide that is post-translationally cleaved at an internal bond between Arg 227 and Ser 228. The beta subunit corresponds to residues 23-227. The alpha subunit corresponds to residues 228-449. Overexpression of Clusterin appears to be more common in late stages of mammary tumor progression. Clusterin markedly influences Amyloid structure and neuritic toxicity in vivo and may influence Alzheimer s pathogenesis.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A portion of amino acids 150-300 was used as the immunogen for the Apolipoprotein J antibody.
Isotype	kappa, Mouse IgG2c
Species Reactivity	Human
Note	Optimal dilution of the Apolipoprotein J antibody should be determined by the researcher.

Uniprot	P10909

Format	Purified
Purity	Protein A/G affinity
Storage	Aliquot the Apolipoprotein J antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC-P
Description	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17123271	V9375SAF, V9375SAF-100UG	100ug	$539		Add to Cart

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