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Home / Primary Antibodies / Monoclonal Antibodies

CD21 Antibody

SKU : BHA17125603

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NSJ Bioreagents

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Mfr.No.	V3778SAF, V3778SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Recognizes a protein of 140kDa, which is identified as the complement receptor 2 (CR2)/CD21. Its epitope is located in 5-8 short consensus repeats (SCRs). This mAb is highly specific to CR2 and shows no cross-reaction with CR1. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A portion of amino acids 44-196 were used as the immunogen for the CD21 antibody.
Isotype	kappa, Mouse IgG1
Species Reactivity	Human
Note	Optimal dilution of the CD21 antibody should be determined by the researcher.

Uniprot	P20023

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the CD21 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	ELISA, IHC-P
Description	ELISA (order BSA/sodium azide-free format for coating),Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17125603	V3778SAF, V3778SAF-100UG	100ug	$539		Add to Cart

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