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Home / Primary Antibodies / Monoclonal Antibodies

Nix Antibody / BNIP3L

SKU : BHA17109526

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NSJ Bioreagents

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Mfr.No.	RQ4749
Clonality	Monoclonal
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like' (BNIP3L), also called NIP3-like protein X (Nix) induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor. (UniProt)
Formulation	Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host	Rabbit
Immunogen Region	A synthetic peptide specific to human Nix / BNIP3L was used as the immunogen for the Nix antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	Nix
Uniprot	O60238
Clone No	ABIB-2

Format	Purified
Purification	Affinity purified
Storage	Store the Nix antibody at -20°C.

Applications	WB
Dilution	Western blot: 1:500-1:2000

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17109526	RQ4749	100ul	$439		Add to Cart

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