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Home / Primary Antibodies / Polyclonal Antibodies

SSB Antibody / Sjoegren syndrome type B antigen / Lupus La protein

SKU : BHA17118993

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NSJ Bioreagents

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Mfr.No.	RQ6579
Cellular Localization	Nuclear
Clonality	Polyclonal (rabbit origin)
Description	Sjogren syndrome type B antigen (SS-B) also known as Lupus La protein is a protein that in humans is encoded by the SSB gene. The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.
Host	Rabbit
Immunogen Region	Recombinant human protein (amino acids D6-L283) was used as the immunogen for the SSB antibody.
Isotype	Rabbit IgG
Reactivity	Human
Recombinant	No

Antigen	SSB
Uniprot	P05455

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the SSB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	Direct ELISA, FACS, IF, IHC-P, WB
Dilution	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Immunofluorescence (FFPE): 5ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA17118993	RQ6579	100ug	$439		Add to Cart

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